Application
Western blot analysis of extracts from JK cells and K562 cells using DRP1 (Phospho-Ser637) Antibody. The lane on the right is treated with the antigen-specific peptide.| Product Name | DRP1 (phospho Ser637) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DLP1, DNM1L, DRP1, DVLP, Dymple |
| Product description | Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally regulated apoptosis during neural tube formation.1) Shin H.-W., J. Biochem. 122:525-530(1997). |
| Immunogen | DRP1 (phospho Ser637) antibody was raised against a peptide sequence around phosphorylation site of Serine 637 (K-L-S (p)-A-R) derived from Human DRP1. |
| Modification | Phosphoralated |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:500~1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | DNM1L |
|---|---|
| Alternative Names | DLP1 DNM1L DRP1 DVLP Dymple |
| Molecular Weight(MW) | 82 kDa |
| Tissue Specificity | The antibody detects endogenous levels of DRP1 only when phosphorylated at serine 637. |
| Entrez Gene | 10059 |
|---|---|
| Protein Accession | NP_036192.2 |
Application
Western blot analysis of extracts from JK cells and K562 cells using DRP1 (Phospho-Ser637) Antibody. The lane on the right is treated with the antigen-specific peptide.| Application Notes | Western Blot: 1:500~1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Data sheet for OM277380