Application
Antibody used in WB on Hum. Fetal Muscle at 1 ug/ml.Application
Antibody used in WB on Hum. Fetal Lung at 1 ug/ml.Application
Antibody used in WB on Human Placenta at 0.2-1 ug/ml.| Product Name | EDAR Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | EDAR, DL, ED1R, ED3, ED5, EDA-A1R, EDA1R, EDA3, HRM1, ECTD10A, ECTD10B |
| Product description | EDAR is a member of the tumor necrosis factor receptor family. It is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in the gene encoding EDAR result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.1) RamaDevi, A.R., (2008) Br. J. Dermatol. 158 (1), 163-167. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human EDAR. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| EDAR antibody can be used for detection of EDAR by ELISA at 1:12500. EDAR antibody can be used for detection of EDAR by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | EDAR |
|---|---|
| Alternative Names | EDAR DL ED1R ED3 ED5 EDA-A1R EDA1R EDA3 HRM1 ECTD10A ECTD10B |
| Molecular Weight(MW) | 48 kDa |
Application
Antibody used in WB on Hum. Fetal Muscle at 1 ug/ml.
Application
Antibody used in WB on Hum. Fetal Lung at 1 ug/ml.
Application
Antibody used in WB on Human Placenta at 0.2-1 ug/ml.| Positive Control | 1) Cat. No. 1309 - Human Placenta Lysate |
|---|---|
| Application Notes | EDAR antibody can be used for detection of EDAR by ELISA at 1:12500. EDAR antibody can be used for detection of EDAR by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store EDAR antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
