Application
Western blot analysis of EFCAB4A in human lung tissue lysate with EFCAB4A antibody at (A) 1 and (B) 2 μg/mL.| Product Name | EFCAB4A Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | EFCAB4A Antibody: CRACR2B, CRACR2B, EF-hand calcium-binding domain-containing protein 4A, Calcium release-activated calcium channel regulator 2B, CRAC channel regulator 2B |
| Product description | EFCAB4A Antibody: EFCAB4A, also known as Calcium release-activated calcium channel regulator 2B, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation, but the detailed function is still under investigation. It is likely to play a similar role as the related protein EFCAB4B, which acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration.1) Srikanth S, Jung HJ, Kim KD, et al. A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cells. Nat. Cell. Biol.2010; 12:436-46. |
| Immunogen | EFCAB4A antibody was raised against a 15 amino acid synthetic peptide near the center of human EFCAB4A. The immunogen is located within amino acids 290 - 340 of EFCAB4A. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| EFCAB4A antibody can be used for detection of EFCAB4A by Western blot at 1 - 2 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | EFCAB4A |
|---|---|
| Alternative Names | EFCAB4A Antibody: CRACR2B CRACR2B EF-hand calcium-binding domain-containing protein 4A Calcium release-activated calcium channel regulator 2B CRAC channel regulator 2B |
Application
Western blot analysis of EFCAB4A in human lung tissue lysate with EFCAB4A antibody at (A) 1 and (B) 2 μg/mL.| Positive Control | 1) Cat. No. 1302 - Human Lung Tissue Lysate |
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| Application Notes | EFCAB4A antibody can be used for detection of EFCAB4A by Western blot at 1 - 2 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | EFCAB4A antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | EFCAB4A Antibody is supplied in PBS containing 0.02% sodium azide. |
