Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA1) Sheikh M. S., Fernandez-Salas E., Yu M., Hussain A., Fornace A. J. Jr. J. Biol. Chem. 274:16487-16493 (1999) Mendell J. T., Medghalchi S. M., Lake R. G., Noensie E. N., Dietz H. C. Mol. Cell. Biol. 20:8944-8957 (2000)
Immunogen
Eif1 antibody was raised against a peptide sequence around aa. 4~8 (Q-N-L-N-T) derived from Drosophila Eif1.