Eukaryotic translation initiation factor 4E-binding protein 2, 4E-BP2, eIF4E-binding protein 2, EIF4EBP2
Product description
This gene encodes a member of the eukaryotic translation
initiation factor 4E binding protein family. The gene products of
this family bind eIF4E and inhibit translation initiation. However,
insulin and other growth factors can release this inhibition via a
phosphorylation-dependent disruption of their binding to eIF4E.
Regulation of protein production through these gene products have
been implicated in cell proliferation, cell differentiation and
viral infection.1) Bailey, S.D., et al. Diabetes Care (2010) In press :
Immunogen
This EIF4EBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-115 amino acids from the C-terminal region of human EIF4EBP2.
Western blot analysis of lysate from human brain tissue lysate, using EIF4EBP2 Antibody at 1:1000 at each lane.
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.