Eukaryotic translation initiation factor 4E transporter, 4E-T, eIF4E transporter, Eukaryotic translation initiation factor 4E nuclear import factor 1, EIF4ENIF1
Product description
The protein encoded by this gene is a nucleocytoplasmic
shuttle protein for the translation initiation factor eIF4E. This
shuttle protein interacts with the importin alpha-beta complex to
mediate nuclear import of eIF4E. It is predominantly cytoplasmic;
its own nuclear import is regulated by a nuclear localization
signal and nuclear export signals. Multiple transcript variants
encoding different isoforms have been found for this gene.1) Suzuki, Y., et al. J. Biol. Chem. 284(51):35597-35604(2009)
Immunogen
This EIF4ENIF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80-108 amino acids from the N-terminal region of human EIF4ENIF1.
Western blot analysis in WiDr cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.