Elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA.1) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010)Martincic, K., et al. Nat. Immunol. 10(10):1102-1109(2009) Simone, F., et al. Blood 101(6):2355-2362(2003) Simone, F., et al. Blood 98(1):201-209(2001) Shilatifard, A., et al. Proc. Natl. Acad. Sci. U.S.A. 94(8):3639-3643(1997)
Immunogen
This ELL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 450-479 amino acids from the C-terminal region of human ELL2.
Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.