Application
Western blot analysis of ELOVL7 in human liver tissue lysate with ELOVL7 antibody at 1 μg/mL.Application
Immunofluorescence of ELOVL7 in human liver tissue with ELOVL7 antibody at 20 μg/mL.Application
Immunohistochemistry of ELOVL7 in human liver tissue with ELOVL7 antibody at 5 μg/mL.| Product Name | ELOVL7 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ELOVL7 Antibody: Elongation of very long chain fatty acids protein 7, 3-keto acyl-CoA synthase ELOVL7, ELOVL FA elongase 7 |
| Product description | ELOVL7 Antibody: Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 7 (ELOVL7) is a member of fatty acyl-CoA elongase gene family that elongates saturated very-long-chain fatty acids (SVLFA, C20:0-) and has been suggested to be involved in prostate cancer growth through saturated long-chain fatty acid metabolism. The metabolic pathways of long-chain fatty acids play an important role in the maintenance of membrane lipid composition and the generation of cell signaling precursor molecules such as eicosanoids and sphingosine-1 phosphate. Overexpression of ELOVL7 results in lipid accumulation in differentiated adipocytes; its expression is regulated by the microRNA miR-219.1) Tamura K, Makino A, Hullin-Matsuda F, et al. Novel lipogenic enzyme ELOVL7 is involved in prostate cancer growth through saturated long-chain fatty acid metabolism. Cancer Res.2009; 69:8133-40. |
| Immunogen | ELOVL7 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human ELOVL7. The immunogen is located within amino acids 40 - 90 of ELOVL7. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| ELOVL7 antibody can be used for detection of ELOVL7 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ELOVL7 |
|---|---|
| Alternative Names | ELOVL7 Antibody: Elongation of very long chain fatty acids protein 7 3-keto acyl-CoA synthase ELOVL7 ELOVL FA elongase 7 |
| Sequence Similarities | 2) Cat. No. 10-201 - Human Liver Tissue Slide |
| Entrez Gene | 79993 |
|---|---|
| Protein Accession | NP_001098028 |
Application
Western blot analysis of ELOVL7 in human liver tissue lysate with ELOVL7 antibody at 1 μg/mL.
Application
Immunofluorescence of ELOVL7 in human liver tissue with ELOVL7 antibody at 20 μg/mL.
Application
Immunohistochemistry of ELOVL7 in human liver tissue with ELOVL7 antibody at 5 μg/mL.| Positive Control | 1) Cat. No. 1304 - Human Liver Tissue Lysate |
|---|---|
| Application Notes | ELOVL7 antibody can be used for detection of ELOVL7 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | ELOVL7 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | ELOVL7 Antibody is supplied in PBS containing 0.02% sodium azide. |
