Application
Western blot analysis in Y79 cell line lysates (35ug/lane).| Product Name | EPB49 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Dematin, Dematin actin-binding protein, Erythrocyte membrane protein band 49, DMTN, DMT, EPB49 |
| Product description | Dematin, or EPB49, is an actin-bundling protein originally identified in the erythroid membrane skeleton. Its actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase and is restored after dephosphorylation (Rana et al., 1993 [PubMed 8341682]).1) Vugmeyster, L., et al. J. Biomol. NMR 47(2):155-162(2010) |
| Immunogen | This EPB49 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-277 amino acids from the Central region of human EPB49. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | DMTN |
|---|---|
| Alternative Names | Dematin Dematin actin-binding protein Erythrocyte membrane protein band 49 DMTN DMT EPB49 |
| Molecular Weight(MW) | 46 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Bovine |
Application
Western blot analysis in Y79 cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
