Application
Western blot analysis of EphA10 in 293 cell lysate with EphA10 antibody at (A) 1 μg/mL and (B) 2 μg/mL.| Product Name | EphA10 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | EphA10 Antibody: Ephrin type-A receptor 10 |
| Product description | EphA10 Antibody: Eph receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important mediators of cell-cell communication regulating cell attachment, shape, and mobility of neuronal and endothelial cells in central nervous system function and in development. Eph receptors can be divided into two subgroups: EphA and EphB. In mammals, the EphA class consists of eight members (EphA 1-7 and 10) that in general bind to ephrin-A members linked to the cell membrane through a glycosylphosphatidylinositol linkage. The EphB class consists of six members (EphB 1-6) that in general bind ephrin-B members that transverse the cell membrane. The Ephrin / EPH signaling pathway networks with the WNT signaling pathway during embryogenesis, tissue regeneration, and carcinogenesis. Recent studies show that Eph/EFN might be relevant in normal B-cell biology and could represent new potential prognostic markers and therapeutic targets for CLL.1) Flanagan JG and Vanderhaeghen P. The ephrins and Eph receptors in neural development. Annu. Rev. Neurosci.1998;.21:309-45. |
| Immunogen | EphA10 antibody was raised against a 14 amino acid synthetic peptide of near the amino terminus of human EphA10. The immunogen is located within amino acids 120 - 170 of EphA10. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| EphA10 antibody can be used for detection of EphA10 by Western blot at 1 - 2 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | EPHA10 |
|---|---|
| Alternative Names | EphA10 Antibody: Ephrin type-A receptor 10 |
| Entrez Gene | 284656 |
|---|---|
| Protein Accession | NP_001092909 |
Application
Western blot analysis of EphA10 in 293 cell lysate with EphA10 antibody at (A) 1 μg/mL and (B) 2 μg/mL.| Positive Control | 1) Cat. No. 1210 - 293 Cell Lysate |
|---|---|
| Application Notes | EphA10 antibody can be used for detection of EphA10 by Western blot at 1 - 2 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | EphA10 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | EphA10 Antibody is supplied in PBS containing 0.02% sodium azide. |
