Application
Western blot analysis of extracts from JK cells (Lane 2), using EPHA7 (Phospho-Tyr791) Antibody. The lane on the left is treated with antigen-specific peptide.| Product Name | EPHA7 (phospho Tyr791) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | EHK3, EK11, HEK11 |
| Product description | Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion. Has a repellent activity on axons and is for instance involved in the guidance of corticothalamic axons and in the proper topographic mapping of retinal axons to the colliculus.1) Fox G.M., Oncogene 10:897-905(1995). |
| Immunogen | EPHA7 (phospho Tyr791) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 791 (A-V-Y (p)-T-T) derived from Human EPHA7 . |
| Modification | p-Tyr791 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:500~1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | EPHA7 |
|---|---|
| Alternative Names | EHK3 EK11 HEK11 |
| Molecular Weight(MW) | 112 kDa |
| Tissue Specificity | The antibody detects endogenous levels of EPHA7only when phosphorylated at tyrosine 791. |
| Entrez Gene | 2045 |
|---|---|
| Protein Accession | NP_004431.1 |
Application
Western blot analysis of extracts from JK cells (Lane 2), using EPHA7 (Phospho-Tyr791) Antibody. The lane on the left is treated with antigen-specific peptide.| Application Notes | Western Blot: 1:500~1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
