c-erbB-2 is a receptor tyrosine kinase of the c-erbB family. It is closely related in structure to the epidermal growth factor receptor. c-erbB-2 oncoprotein is detectable in a proportion of breast and other adenocarconomas, as well as transitional cell carcinomas. In the case of breast cancer, expression determined by immunohistochemistry has been shown to be associated with poor prognosis.
Immunogen
ERBB2 monoclonal antibody was raised against a synthetic peptide corresponding to the C-Terminus of human ERBB2 (Human).
Key Feature
Clonality
Monoclonal
Isotype
IgG1, k
Host Species
Mouse
Tested Applications
IHCWB
ERBB2 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.:
Immunohistochemistry staining of ERBB2 in human breast tissue using ERBB2 monoclonal Antibody.
Application Notes
ERBB2 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.:
Additional Information
Form
Liquid
Storage Instructions
Store ERBB2 antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles.