DNA repair protein complementing XP-G cells, 31--, DNA excision repair protein ERCC-5, Xeroderma pigmentosum group G-complementing protein, ERCC5, ERCM2, XPG, XPGC
Product description
Excision repair cross-complementing rodent repair
deficiency, complementation group 5 (xeroderma pigmentosum,
complementation group G) is involved in excision repair of
UV-induced DNA damage. Mutations cause Cockayne syndrome, which is
characterized by severe growth defects, mental retardation, and
cachexia. Multiple alternatively spliced transcript variants
encoding distinct isoforms have been described, but the biological
validity of all variants has not been determined. [provided by
RefSeq].1) Figl, A., et al. Mutat. Res. 702(1):8-16(2010)
Immunogen
This ERCC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1151-1178 amino acids from the C-terminal region of human ERCC5.
DNA repair protein complementing XP-G cells 31-- DNA excision repair protein ERCC-5 Xeroderma pigmentosum group G-complementing protein ERCC5 ERCM2 XPG XPGC
Western Blot at 1:1000 dilution + Jurkat whole cell lysate Lysates/proteins at 20 ug per lane.
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.