ERGIon Channel2 possibly play role in transport between endoplasmic reticulum and Golgi. ERGIon Channel2 is downregulated in prostate cancer. ERGIon Channel2 may play an important role in the growth and tumorigenicity of PC-3 prostate tumor cells. Ectopic expression of a partial sequence of ERGIon Channel2 as a VP22-fusion protein in prostate cancer cell line, PC-3, induced cellular senescence. Interferon-beta (IFN-beta) and a number of IFN-inducible genes were upregulated by the ERGIon Channel2-VP22 fusion protein.1) Thomas J. Nelson, et al., (2007) J Biol Chem 282:31238.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ERG Ion Channel 2.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAWB
ERG Ion Channel 2 antibody can be used for detection of ERG Ion Channel 2 by ELISA at 1:62500. ERG Ion Channel 2 antibody can be used for detection of ERG Ion Channel 2 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
ERG Ion Channel 2 antibody can be used for detection of ERG Ion Channel 2 by ELISA at 1:62500. ERG Ion Channel 2 antibody can be used for detection of ERG Ion Channel 2 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store ERG Ion Channel 2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt