Application
Western blot analysis in 293,HepG2 cell line lysates (35ug/lane).Application
ERV3 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.| Product Name | ERV3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Endogenous retrovirus group 3 member 1 Env polyprotein, ERV-3 envelope protein, ERV3 envelope protein, ERV3-1 envelope protein, Envelope polyprotein, HERV-R envelope protein, ERV-R envelope protein, HERV-R_7q212 provirus ancestral Env polyprotein, Surface |
| Product description | The human genome includes many retroelements including the human endogenous retroviruses (HERVs). ERV3, one of the most studied HERVs, is thought to have integrated 30 to 40 million years ago and is present in higher primates with the exception of gorillas. Taken together, the observation of genome conservation, the detection of transcript expression, and the presence of conserved ORFs is circumstantial evidence for a functional role. A functional role is also suggested by the observation that downregulation of ERV3 is reported in choriocarcinoma. [provided by RefSeq].1) Andersson, A.C., et al. J. Virol. 79(14):9270-9284(2005) |
| Immunogen | This ERV3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 445-474 amino acids from the C-terminal region of human ERV3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ERV3-1 |
|---|---|
| Alternative Names | Endogenous retrovirus group 3 member 1 Env polyprotein ERV-3 envelope protein ERV3 envelope protein ERV3-1 envelope protein Envelope polyprotein HERV-R envelope protein ERV-R envelope protein HERV-R_7q212 provirus ancestral Env polyprotein Surface |
| Molecular Weight(MW) | 68 kDa |
Application
Western blot analysis in 293,HepG2 cell line lysates (35ug/lane).
Application
ERV3 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.| Application Notes | For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
