May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function.1) Gorbea C., Pratt G., Ustrell V., Bell R., Sahasrabudhe S., Hughes R. E., Rechsteiner M. J. Biol. Chem. 285:31616-31633 (2010)
Immunogen
ESA (FLOT2) antibody was raised against a peptide sequence around aa.420~424 (I-K-K-A-T) derived from Human ESA (FLOT2).