Application
Antibody used in WB on Human 293T at 0.2-1 ug/ml.Application
Antibody used in IHC on Human Spleen at 5 ug/ml.| Product Name | ETV5 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ETV5, ERM |
| Product description | ETV5 Contains 1 ETS DNA-binding domain and belongs to the ETS family. The ETV5 gene expression is regulated by the conventional PKC (cPKC) pathway.ETV5 is subject to SUMO modification and this post-translational modification causes inhibition of transcription-enhancing activity Phosphorylated ETV5 and the actin cytoskeleton regulate CD44-mediated hyaluronan binding in myeloid cells. ERMs (ezrin/radixin/moesin) function as adaptor molecules in the interactions of adhesion receptors and intracellular tyrosine kinases. ETV5 can cooperate with c-Jun and has a role in progression of breast cancer1) Degerny, C., (2005) J. Biol. Chem. 280 (26), 24330-24338. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ETV5. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| ETV5 antibody can be used for detection of ETV5 by ELISA at 1:62500. ETV5 antibody can be used for detection of ETV5 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | DogHumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ETV5 |
|---|---|
| Alternative Names | ETV5 ERM |
| Molecular Weight(MW) | 58 kDa, 58 kDa |
Application
Antibody used in WB on Human 293T at 0.2-1 ug/ml.
Application
Antibody used in IHC on Human Spleen at 5 ug/ml.| Positive Control | 1) 293T Cell Lysate |
|---|---|
| Application Notes | ETV5 antibody can be used for detection of ETV5 by ELISA at 1:62500. ETV5 antibody can be used for detection of ETV5 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store ETV5 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
