Members of the F-box protein family, such as FBXL19, are
characterized by an approximately 40-amino acid F-box motif. SCF
complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM
603134), and F-box proteins, act as protein-ubiquitin ligases.
F-box proteins interact with SKP1 through the F box, and they
interact with ubiquitination targets through other protein
interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied
by OMIM].1) Martin, J., et al. Nature 432(7020):988-994(2004)
Immunogen
This FBXL19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 543-570 amino acids from the C-terminal region of human FBXL19.
Western blot analysis in mouse testis tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.