Application
Western blot analysis in mouse heart tissue lysates (35ug/lane).| Product Name | FBXO18 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | F-box only protein 18, F-box DNA helicase 1, FBXO18, FBH1, FBX18 |
| Product description | This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. It contains an F-box motif and seven conserved helicase motifs, and has both DNA-dependent ATPase and DNA unwinding activities. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.1) Turnbull, C., et al. Nat. Genet. 42(6):504-507(2010) |
| Immunogen | This FBXO18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 741-769 amino acids from the C-terminal region of human FBXO18. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Mouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | FBXO18 |
|---|---|
| Alternative Names | F-box only protein 18 F-box DNA helicase 1 FBXO18 FBH1 FBX18 |
| Molecular Weight(MW) | 118 kDa |
Application
Western blot analysis in mouse heart tissue lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
