This gene encodes a member of the F-box protein family
which is characterized by an approximately 40 amino acid motif, the
F-box. The F-box proteins constitute one of the four subunits of
the ubiquitin protein ligase complex called SCFs
(SKP1-cullin-F-box), which function in phosphorylation-dependent
ubiquitination. The F-box proteins are divided into 3 classes: Fbws
containing WD-40 domains, Fbls containing leucine-rich repeats, and
Fbxs containing either different protein-protein interaction
modules or no recognizable motifs. The protein encoded by this gene
belongs to the Fbxs class. Two transcript variants encoding
different isoforms exist for this gene.1) Borziak, K., et al. Bioinformatics 23(19):2518-2521(2007)
Immunogen
This FBXO22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 320-347 amino acids from the C-terminal region of human FBXO22.
Western blot analysis in mouse heart tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.