Members of the F-box protein family, such as FBXO31, are
characterized by an approximately 40-amino acid F-box motif. SCF
complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM
603134), and F-box proteins, act as protein-ubiquitin ligases.
F-box proteins interact with SKP1 through the F box, and they
interact with ubiquitination targets through other protein
interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied
by OMIM].1) Rivadeneira, F., et al. Nat. Genet. 41(11):1199-1206(2009)
Immunogen
This FBXO31 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 310-338 amino acids from the Central region of human FBXO31.
Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.