Western blot analysis of FCAR using rabbit polyclonal FCAR Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FCAR gene.
This gene is a member of the immunoglobulin gene
superfamily and encodes a receptor for the Fc region of IgA. The
receptor is a transmembrane glycoprotein present on the surface of
myeloid lineage cells such as neutrophils, monocytes, macrophages,
and eosinophils, where it mediates immunologic responses to
pathogens. It interacts with IgA-opsonized targets and triggers
several immunologic defense processes, including phagocytosis,
antibody-dependent cell-mediated cytotoxicity, and stimulation of
the release of inflammatory mediators. Multiple alternatively
spliced transcript variants encoding different isoforms have been
described for this gene.1) Vuong, M.T., et al. Kidney Int. (2010) In press :
Immunogen
This FCAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-84 amino acids from the Central region of human FCAR.
Western blot analysis of FCAR using rabbit polyclonal FCAR Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FCAR gene.
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.