Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.1) Ravetch J.V.,et al.J. Exp. Med. 170:481-497(1989).
Immunogen
This FCGR3B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 12-47 amino acids from the N-terminal region of human FCGR3B.
Western blot analysis of lysate from HL-60 cell line, using FCGR3B Antibody at 1:1000.
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.