Application
Antibody used in WB on Human Raji at 0.2-1 ug/ml.| Product Name | FGD1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome.1) Lebel, R.R., et al., (2002) Clin. Genet. 61 (2), 139-145. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FGD1. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| FGD1 antibody can be used for detection of FGD1 by ELISA at 1:312500. FGD1 antibody can be used for detection of FGD1 by western blot at 2.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | FGD1 |
|---|---|
| Alternative Names | FGD1 AAS FGDY MRXS16 ZFYVE3 |
| Molecular Weight(MW) | 107 kDa |
Application
Antibody used in WB on Human Raji at 0.2-1 ug/ml.| Positive Control | 1) Cat. No. 1207 - Raji Cell Lysate |
|---|---|
| Application Notes | FGD1 antibody can be used for detection of FGD1 by ELISA at 1:312500. FGD1 antibody can be used for detection of FGD1 by western blot at 2.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store FGD1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
