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FIBB Antibody

Catalog Number:OM278856
OM278856
Discount Price
OM278856-100ul
1~2 Week
100ul
OM278856-50ul
50ul
OM278856-20ul
20ul
1~2 Week
Product Profile
Product Name FIBB Antibody
Antibody Type Primary Antibodies
Product description FIBB is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.1) Sun,A., Acta Cardiol 64 (3), 357-361 (2009)
Immunogen This FIBB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 330-357 amino acids from the C-terminal region of human FIBB.
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications IHC-PWB
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50
Species Reactivity HumanMouse
Concentration 1mg/ml
Purification Unpurified
Target Information
Gene Symbol FGB
Alternative Names Fibrinogen beta chain
Fibrinopeptide B
Fibrinogen beta chain
FGB
Molecular Weight(MW) 56 kDa
Sequence Similarities Predicted species reactivity based on immunogen sequence: Rat
Database Links
Entrez Gene 2244
Protein Accession P02675
Application

Application

FIBB Antibody IHC analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.

Application

Western blot analysis of FIBB antibody in mouse liver tissue lysates (35ug/lane)
Application Notes For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50
Additional Information
Form Liquid
Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
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