Application
Western blot analysis of extract from 293, HeLa cells using Fibrillarin Antibody.| Product Name | Fibrillarin Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.1) Lischwe M. A., Ochs R. L., Reddy R., Cook R. G., Yeoman L. C., Tan E. M., Reichlin M., Busch H. J. Biol. Chem. 260:14304-14310 (1985) Yanagida M., Hayano T., Yamauchi Y., Shinkawa T., Natsume T., Isobe T., Takahashi N. J. Biol. Chem. 279:1607-1614 (2004) Wang Y., Liu J., Zhao H., Lue W., Zhao J., Yang L., Li N., Du X., Ke Y. Biochim. Biophys. Acta 1773:863-868 (2007) |
| Immunogen | Fibrillarin antibody was raised against a peptide sequence around aa.297~301 ( L-T-L-E-P) derived from Human Fibrillarin. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:500~1:1000 | |
| Species Reactivity | MouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | FBL |
|---|---|
| Alternative Names | FIB FLRN RNU3IP1 FBL FIB |
| Molecular Weight(MW) | 37 kDa |
| Tissue Specificity | This antibody detects endogenous level of total Fibrillarin protein. |
| Entrez Gene | 2091 |
|---|---|
| Protein Accession | NP_001427.2 |
Application
Western blot analysis of extract from 293, HeLa cells using Fibrillarin Antibody.| Application Notes | Western Blot: 1:500~1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
