Fidgetin is a member of the 'meiotic' or subfamily-7 group of ATPases associated with diverse cellular activities (AAA proteins). Fidgetin can interact with itself and this interaction can be abolished by truncating either the N- or C-terminus of the protein. AAA proteins are molecular chaperones that facilitate membrane fusion, proteolysis, peroxisome biogenesis, endosome sorting and meiotic spindle formation.1) Bailey, S.D., et al. Diabetes Care (2010) In press :
Immunogen
This FIGN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 615-643 amino acids from the C-terminal region of human FIGN.
Western blot analysis in mouse kidney tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.