Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth When expressed in tumor-associated vasculature.1) Notaridou, M., et al. Int. J. Cancer (2010) In press :
Immunogen
This FIL1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-224 amino acids from the N-terminal region of human FIL1L.
Filamin A-interacting protein 1-like 130 kDa GPBP-interacting protein 90 kDa GPBP-interacting protein Protein down-regulated in ovarian cancer 1 DOC-1 FILIP1L COL4A3BPIP DOC1 GIP90
Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.