FOXA3 encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. The crystal structure of a similar protein in rat has been resolved.1) Kaestner, K.H. et al., (2000) Trends Endocrinol. Metab. 11 (7), 281-285.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FOXA3.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAIHCWB
FOXA3 antibody can be used for detection of FOXA3 by ELISA at 1:62500. FOXA3 antibody can be used for detection of FOXA3 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
FOXA3 antibody can be used for detection of FOXA3 by ELISA at 1:62500. FOXA3 antibody can be used for detection of FOXA3 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store FOXA3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.