Application
Immunohistochemical analysis of paraffin-embedded human brain tissue using FRS2 (Phospho-Tyr436) antibody (left) or the same antibody preincubated with blocking peptide (right).Application
Western blot analysis of extracts from HuvEc cells (Lane 2) and JK cells (Lane 3), using FRS2 (Phospho-Tyr436) Antibody. The lane on the left is treated with antigen-specific peptide.| Product Name | FRS2 (phospho Tyr436) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SNT-1, SNT2, FGFR signalling adaptor |
| Product description | FRS2 is an adaptor protein involved in fibroblast growth factor receptor (FGFR) signaling. Plays an important role in linking FGFR and nerve growth factor receptors with Ras/MAPK signaling pathways.1) Xu H., J. Biol. Chem. 273:17987-17990(1998). |
| Immunogen | FRS2 (phospho Tyr436) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 436 (L-N-Y (p)-I-Q) derived from Human FRS2 . |
| Modification | p-Tyr436 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | FRS2 |
|---|---|
| Alternative Names | SNT-1 SNT2 FGFR signalling adaptor |
| Molecular Weight(MW) | 65 kDa |
| Tissue Specificity | The antibody detects endogenous levels of FRS2 only when phosphorylated at tyrosine 436. |
| Entrez Gene | 10818 |
|---|---|
| Protein Accession | NP_001036020.1 |
Application
Immunohistochemical analysis of paraffin-embedded human brain tissue using FRS2 (Phospho-Tyr436) antibody (left) or the same antibody preincubated with blocking peptide (right).
Application
Western blot analysis of extracts from HuvEc cells (Lane 2) and JK cells (Lane 3), using FRS2 (Phospho-Tyr436) Antibody. The lane on the left is treated with antigen-specific peptide.| Application Notes | Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
