This gene encodes one of three GA-binding protein
transcription factor subunits which functions as a DNA-binding
subunit. Since this subunit shares identity with a subunit encoding
the nuclear respiratory factor 2 gene, it is likely involved in
activation of cytochrome oxidase expression and nuclear control of
mitochondrial function. This subunit also shares identity with a
subunit constituting the transcription factor E4TF1, responsible
for expression of the adenovirus E4 gene. Because of its
chromosomal localization and ability to form heterodimers with
other polypeptides, this gene may play a role in the Down Syndrome
phenotype. Two transcript variants encoding the same protein have
been found for this gene.1) Henderson, A.J., et al. Thorax 65(10):897-902(2010)
Immunogen
This GABPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-311 amino acids from the Central region of human GABPA.
Western blot analysis in CEM cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.