Application
Immunohistochemistry of GBP5 in human liver tissue with GBP5 antibody at 2.5 μg/ml.Application
Immunofluorescence of GBP5 in human liver tissue with GBP5 antibody at 20 μg/ml.Application
Western blot analysis of GBP5 in rat liver tissue lysate with GBP5 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.| Product Name | GBP5 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | GBP5 Antibody: The guanylate-binding proteins (GBPs) are a family of interferon-induced GTP-binding proteins function in innate immunity against microbial and viral pathogens. In humans, there are seven GBPs from hGBP1 to hGBP7. Human GBP1 and GBP2 have been shown to exhibit antiviral activity as well as being able to regulate the inhibition of proliferation and invasion of endothelial cells in response to interferon (IFN). GBP5 promotes selective NALP3 inflammasome responses to pathogenic bacteria and soluble but not crystalline inflammasome priming agents.1) Vestal DJ. The guanylate-binding proteins (GBPs): proinflammatory cytokine-induced members of the dynamin superfamily with unique GTPase activity. J. Interferon Cytokine Res. 2005; 25:435-43. |
| Immunogen | GBP5 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human GBP5 . The immunogen is located within the last 50 amino acids of GBP5. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| GBP5 Antibody can be used for detection of GBP5 by Western blot at 1 μg/mL. | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | GBP5 |
|---|---|
| Alternative Names | GBP5 Antibody: GBP-5 Guanylate-binding protein 5 GBP-TA antigen GBP-5 |
| Molecular Weight(MW) | Predicted: 64 kDa Observed: 66 kDa |
| Sequence Similarities | 2) Cat. No. 10-201 - Human Liver Tissue Slide |
| Tissue Specificity | GBP5 antibody is predicted to not cross-react with other GBP family members. |
Application
Immunohistochemistry of GBP5 in human liver tissue with GBP5 antibody at 2.5 μg/ml.
Application
Immunofluorescence of GBP5 in human liver tissue with GBP5 antibody at 20 μg/ml.
Application
Western blot analysis of GBP5 in rat liver tissue lysate with GBP5 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.| Application Notes | GBP5 Antibody can be used for detection of GBP5 by Western blot at 1 μg/mL. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | GBP5 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | GBP5 Antibody is supplied in PBS containing 0.02% sodium azide. |
