N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform A, N-acetylglucosaminyltransferase, I-branching enzyme, IGNT, GCNT2, GCNT5, II, NACGT1
Product description
This gene encodes the enzyme responsible for formation of
the blood group I antigen. The i and I antigens are distinguished
by linear and branched poly-N-acetyllactosaminoglycans,
respectively. The encoded protein is the I-branching enzyme, a
beta-1,6-N-acetylglucosaminyltransferase responsible for the
conversion of fetal i antigen to adult I antigen in erythrocytes
during embryonic development. Mutations in this gene have been
associated with adult i blood group phenotype. Alternatively
spliced transcript variants encoding different isoforms have been
described.1) Twu, Y.C., et al. Blood 110(13):4526-4534(2007)
Immunogen
This GCNT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-240 amino acids from the Central region of human GCNT2.
Western blot analysis in A549 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.