Application
Immunofluorescence of GDF1 in human lung tissue with GDF1 antibody at 20 μg/mL.Application
Western blot analysis of GDF1 in rat lung tissue lysate with GDF1 antibody at (A) 1 and (B) 2 μg/mL.| Product Name | GDF1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | GDF1 Antibody: Growth differentiation factors (GDFs) are members of the transforming growth factor (TGF) superfamily that is involved in embryonic development and adult tissue homeostasis. GDF1 was initially identified as a temporally expressed gene in the mouse central nervous system during embryonic development, with only one isoform detected in adult tissues. GDF1 is required for left-right patterning during development and directly interacts with Nodal, another member of the TGF-beta superfamily. It has been suggested that GDF1 regulates the activity and signaling range of Nodal through direct interaction.1) Massague J. 1990. The transforming growth factor-beta family. Ann. Rev. Cell Biol. 6:597-641. |
| Immunogen | Rabbit polyclonal GDF1 antibody was raised against a 16 amino acid peptide near the amino terminus of human GDF1. The immunogen is located within amino acids 30 - 80 of GDF1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFWB |
| GDF1 antibody can be used for detection of GDF1 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL. | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | GDF1 |
|---|---|
| Alternative Names | GDF1 Antibody: RAI DORV DTGA3GDF-1 |
| Molecular Weight(MW) | 41 kDa |
| Sequence Similarities | 2) Cat. No. 10-101 - Human Lung Tissue Slide |
| Tissue Specificity | GDF1 antibody is predicted to not cross-react with any other members of the growth differentiation factor family. |
Application
Immunofluorescence of GDF1 in human lung tissue with GDF1 antibody at 20 μg/mL.
Application
Western blot analysis of GDF1 in rat lung tissue lysate with GDF1 antibody at (A) 1 and (B) 2 μg/mL.| Application Notes | GDF1 antibody can be used for detection of GDF1 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL. |
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| Form | Liquid |
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| Storage Instructions | GDF1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | GDF1 Antibody is supplied in PBS containing 0.02% sodium azide. |
