Gem-associated protein 4, Gemin-4, Component of gems 4, p97, GEMIN4
Product description
The product of this gene is part of a large complex
localized to the cytoplasm, nucleoli, and to discrete nuclear
bodies called Gemini bodies (gems). The complex functions in
spliceosomal snRNP assembly in the cytoplasm, and regenerates
spliceosomes required for pre-mRNA splicing in the nucleus. The
encoded protein directly interacts with a DEAD box protein and
several spliceosome core proteins. Alternatively spliced transcript
variants have been described, but their biological validity has not
been determined.1) Kim, J.S., et al. Mol. Carcinog. 49(10):913-921(2010)
Immunogen
This GEMIN4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-301 amino acids from the N-terminal region of human GEMIN4.
Western blot analysis in A549 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.