Gem-associated protein 8, Gemin-8, Protein FAM51A1, GEMIN8, FAM51A1
Product description
The protein encoded by this gene is part of the SMN
complex, which is necessary for spliceosomal snRNP assembly in the
cytoplasm and pre-mRNA splicing in the nucleus. The encoded protein
binds to both SMN1 and the GEMIN6/GEMIN7 heterodimer, mediating
their interaction. This protein is found in nuclear Gemini of Cajal
bodies (gems) and in the cytoplasm. Three transcript variants
encoding the same protein have been found for this gene. [provided
by RefSeq].1) Carissimi, C., et al. J. Biol. Chem. 281(48):37009-37016(2006)
Immunogen
This GEMIN8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-239 amino acids from the C-terminal region of human GEMIN8.
Western blot analysis in A549 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.