The enzyme encoded by this gene catalyzes the transfer of
the glutamyl moiety of glutathione to a variety of amino acids and
dipeptide acceptors. The enzyme is composed of a heavy chain and a
light chain, which are derived from a single precursor protein, and
is present in tissues involved in absorption and secretion. This
enzyme is a member of the gamma-glutamyltransferase protein family,
of which many members have not yet been fully characterized and
some of which may represent pseudogenes. This gene is classified as
type I gamma-glutamyltransferase. Multiple alternatively spliced
variants, encoding the same protein, have been identified.1) Speliotes, E.K., et al. Hepatology 52(3):904-912(2010)
Immunogen
This GGT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-152 amino acids from the N-terminal region of human GGT1.
Western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).
Application
Western blot analysis in U251 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.