Application
Immunoflorescence of GLIPR1 in human small intestine tissue with GLIPR1 antibody at 5 μg/mL.Application
Western blot analysis of GLIPR1 in human small intestine tissue lysate with GLIPR1 antibody at 1 μg/ml.| Product Name | GLIPR1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GLIPR1 Antibody: GLIPR, RTVP1, CRISP7, GLIPR, Glioma pathogenesis-related protein 1, Protein RTVP-1, GliPR 1 |
| Product description | The glioma pathogensis-related protein 1 (GLIPR1) is similar to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family (1). GLIPR1 is a tumor suppressor whose expression is regulated by p53; its increased expression is associated with myelomocytic differentiation in macrophages, whereas decreased expression of this gene through gene methylation is associated with prostate cancer (2). The GLIPR1 gene is part of a p53 target gene cluster that includes GLIPR1L1 and GLIPR1L2, two highly homologous proteins whose expression patterns vary (3).1) Murphy EV, Zhang Y, Zhu W, et al. The human glioma pathogenesis-related protein is structurally related to pathogenesis-related proteins and its gene is expressed specifically in brain tumors. Gene 1995; 159:131-5. |
| Immunogen | GLIPR1 antibody was raised against an 18 amino acid peptide near the center of human GLIPR1. The immunogen is located within amino acids 60 - 110 of GLIPR1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFWB |
| GLIPR1 antibody can be used for detection of GLIPR1 by Western blot at 1 - 2 μg/ml. For Immunoflorescence start at 5 μg/mL.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | GLIPR1 |
|---|---|
| Alternative Names | GLIPR1 Antibody: GLIPR RTVP1 CRISP7 GLIPR Glioma pathogenesis-related protein 1 Protein RTVP-1 GliPR 1 |
| Molecular Weight(MW) | Predicted: 29 kDa Observed: 29 kDa |
| Sequence Similarities | 2) Cat. No. 11-801 - Human Small Intestine Tissue Slide |
| Tissue Specificity | GLIPR1 antibody is human and mouse reactive. At least two isoforms of GLIPR1 are known to exist; this antibody will detect both isoforms. This antibody is predicted to not cross-react with other GLIPR or GLIPR-like proteins. |
Application
Immunoflorescence of GLIPR1 in human small intestine tissue with GLIPR1 antibody at 5 μg/mL.
Application
Western blot analysis of GLIPR1 in human small intestine tissue lysate with GLIPR1 antibody at 1 μg/ml.| Positive Control | 1) Cat. No. 1308 - Human Small Intestine Tissue Lysate |
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| Application Notes | GLIPR1 antibody can be used for detection of GLIPR1 by Western blot at 1 - 2 μg/ml. For Immunoflorescence start at 5 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | GLIPR1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | GLIPR1 antibody is supplied in PBS containing 0.02% sodium azide. |
