Granulysin, Lymphokine LAG-2, Protein NKG5, T-cell activation protein 519, GNLY, LAG2, NKG5, TLA519
Product description
The product of this gene is a member of the saposin-like
protein (SAPLIP) family and is located in the cytotoxic granules of
T cells, which are released upon antigen stimulation. This protein
is present in cytotoxic granules of cytotoxic T lymphocytes and
natural killer cells, and it has antimicrobial activity against M.
tuberculosis and other organisms. Alternatively spliced transcript
variants encoding different isoforms have been identified.1) Xing, J., et al. J. Immunol. 185(9):5074-5081(2010)
Immunogen
This GNLY antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-42 amino acids from the N-terminal region of human GNLY.
Western blot analysis in MDA-MB435 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.