Golgin subfamily A member 6A, Golgin linked to PML, Golgin-like protein, GOLGA6A, GLP, GOLGA6
Product description
The Golgi apparatus, which participates in glycosylation
and transport of proteins and lipids in the secretory pathway,
consists of a series of stacked cisternae (flattened membrane
sacs). Interactions between the Golgi and microtubules are thought
to be important for the reorganization of the Golgi after it
fragments during mitosis. The protein encoded by this gene is a
member of the golgin family of proteins, whose members localize to
the Golgi. This gene is found in a large, low copy repeat sequence
or duplicon that is found in multiple copies, that are greather
than 90% similar, on chromosome 15. Duplicons are associated with
deletions, inversions and other chromosome rearrangements that
underlie genomic disease. The protein encoded by this gene is
thought to be a functional golgin protein while the majority of the
related copies of this gene are thought to be transcribed
pseudogenes.1) Ventura, M., et al. Genome Res. 13(9):2059-2068(2003)
Immunogen
This GOLGA6A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 516-543 amino acids from the C-terminal region of human GOLGA6A.
Western blot analysis in 293 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.