GPR15, Brother of Bonzo, G protein-coupled receptor 15, G-protein coupled receptor 15, BOB, Gpr-15
Product description
G protein-coupled receptor GPR15 is an Orphan-A GPCR with an unknown ligand. Coreceptor usage of primary human immunodeficiency virus type 1 (HIV-1) isolates varies according to biological phenotype. The chemokine receptors CCR5 and CXCR4 are the major coreceptors that, together with CD4, govern HIV-1 entry into cells. Some HIV-1, HIV-2, and SIV isolates of different genetic subtypes and biological phenotypes use BOB/GPR15 for productive infection, suggesting that this cofactor may play a role in HIV-1 pathogenesis and transmission.
Immunogen
GPR15 antibody was raised against a peptide located in the C-Terminal cytoplasmic domain of GPR15 (Human).
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAIHC
GPR15 antibody can be used in ELISA, and immunohistochemistry starting at 10 μg/mL.: