GRB7 belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK).1) Depetris, R.S., et al. Nat. Struct. Mol. Biol. 16(8):833-839(2009)
Immunogen
This GRB7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 289-318 amino acids from the Central region of human GRB7.
Western blot analysis of GRB7 Antibody in mouse brain tissue lysates (35ug/lane)
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.