Application
Western blot analysis of Grik3 in human brain tissue lysate with Grik3 antibody at (A) 1 and (B) 2 μg/mL.| Product Name | Grik3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Grik3 Antibody: EAA5, GLR7, GLUR7, GluK3, GluR7a, Glutamate receptor ionotropic, kainate 3, Excitatory amino acid receptor 5 |
| Product description | Grik3 Antibody: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik3, also known as glutamate receptor 7, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Grik3 is highly homologous to the related ionotrophic glutamate receptors Grik2 and Grik1. Grik3 has recently been shown to be an essential subunit of presynaptic kainate autoreceptors at hippocampal mossy fiber synapses as grik3-null mice show significantly reduced short- and long-term synaptic potentiation. Other reports have suggested that different polymorphisms in the Grik3 protein may be associated with neurological defects such as recurrent major depressive disorder and schizophrenia. This Grik3 antibody does not cross-react with Grik2.1) Tanaka K. Functions of glutamate transports in the brain. Neurosci. Res.2000; 37:15-9. |
| Immunogen | Grik3 antibody was raised against a 13 amino acid synthetic peptide near the amino terminus of the human Grik3. The immunogen is located within amino acids 30 - 80 of Grik3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| Grik3 antibody can be used for detection of Grik3 by Western blot at 1 - 2 μg/mL.: |
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| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | GRIK3 |
|---|---|
| Alternative Names | Grik3 Antibody: EAA5 GLR7 GLUR7 GluK3 GluR7a Glutamate receptor ionotropic kainate 3 Excitatory amino acid receptor 5 |
Application
Western blot analysis of Grik3 in human brain tissue lysate with Grik3 antibody at (A) 1 and (B) 2 μg/mL.| Positive Control | 1) Cat. No. 1303 - Human Brain Tissue Lysate |
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| Application Notes | Grik3 antibody can be used for detection of Grik3 by Western blot at 1 - 2 μg/mL.: |
| Form | Liquid |
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| Storage Instructions | Grik3 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Grik3 Antibody is supplied in PBS containing 0.02% sodium azide. |
