Application
Western blot analysis of extracts from Mouse brain cells using GRIN2B (Phospho-Ser1303) Antibody. The lane on the right is treated with the antigen-specific peptide.| Product Name | GRIN2B (phospho Ser1303) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GRIN2B, NMDE2, NME2, NR2B, NR3 |
| Product description | N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.1) Adams S.L., Biochim. Biophys. Acta 1260:105-108(1995). |
| Immunogen | GRIN2B (phospho Ser1303) antibody was raised against a peptide sequence around phosphorylation site of Serine 1303 (Q-H-S (p)-Y-D) derived from Human GRIN2B. |
| Modification | p-Ser1303 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:500~1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | GRIN2B |
|---|---|
| Alternative Names | GRIN2B NMDE2 NME2 NR2B NR3 |
| Molecular Weight(MW) | 170 kDa |
| Tissue Specificity | The antibody detects endogenous levels of GRIN2B only when phosphorylated at serine 1303. |
| Entrez Gene | 2904 |
|---|---|
| Protein Accession | NP_000825.2 |
Application
Western blot analysis of extracts from Mouse brain cells using GRIN2B (Phospho-Ser1303) Antibody. The lane on the right is treated with the antigen-specific peptide.| Application Notes | Western Blot: 1:500~1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
