Application
Immunohistochemistry of GRIP1 in rat brain tissue with GRIP1 antibody at 2.5 μg/ml.Application
Immunofluorescence of GRIP1 in rat brain tissue with GRIP1 antibody at 20 μg/ml.Application
Western blot analysis of GRIP1 in 293 cell lysate with GRIP1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.| Product Name | GRIP1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GRIP1 Antibody: GRIP, Glutamate receptor-interacting protein 1, GRIP-1 |
| Product description | GRIP1 Antibody: Glutamate receptors play an important role in neural plasticity, development and degeneration. The glutamate receptor interacting proteins, GRIP1 and GRIP2, members of the PDZ domain-containing protein family, mediate the trafficking and membrane organization of a number of transmembrane proteins. GRIP1 and GRIP2 specifically bind to the AMPA receptor subunits, GluR 2/3 and are involved in the targeting of GluR 2/3 to the synapse. GRIP1 is expressed in early development before the expression of AMPA receptors, while GRIP2 expression parallels that of AMPA receptors during later developmental stages. GRIP1 and GRIP2 may be involved in the induction of cerebellar long-term depression (LTD).1) Nakanishi S. Molecular diversity of glutamate receptors and implications for brain function. Science 1992; 258:597-603. |
| Immunogen | Rabbit polyclonal GRIP1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human GRIP1. The immunogen is located within the last 50 amino acids of GRIP1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| GRIP1 antibody can be used for detection of GRIP1 by Western blot at 1 - 2 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | GRIP1 |
|---|---|
| Alternative Names | GRIP1 Antibody: GRIP Glutamate receptor-interacting protein 1 GRIP-1 |
| Molecular Weight(MW) | Predicted: 118 kDa Observed: 115 kDa |
Application
Immunohistochemistry of GRIP1 in rat brain tissue with GRIP1 antibody at 2.5 μg/ml.
Application
Immunofluorescence of GRIP1 in rat brain tissue with GRIP1 antibody at 20 μg/ml.
Application
Western blot analysis of GRIP1 in 293 cell lysate with GRIP1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.| Positive Control | 1) Cat. No. 1210 - 293 Cell Lysate |
|---|---|
| Application Notes | GRIP1 antibody can be used for detection of GRIP1 by Western blot at 1 - 2 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | GRIP1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | GRIP1 Antibody is supplied in PBS containing 0.02% sodium azide. |
