| Product description |
Mouse monoclonal [GRP01] to GRIP1The steroid hormones, thyroid hormone, vitamin D, and retinoic acid function by activating specific nuclear receptor proteins found inside of target cells. The activated receptors bind to and activate specific genes, and the products of these activated genes change cellular activities in specific ways, thus constituting the biological response to the hormone. After binding to target genes, the activated nuclear receptors require the assistance of proteins called transcriptional coactivators in order to activate the target genes. GRIP 1 is a novel protein that serves as a transcriptional coactivator for steroid and nuclear hormone receptors. |