Glutathione S-transferase (GSTs) theta 2 (GSTT2) is a
member of a superfamily of proteins that catalyze the conjugation
of reduced glutathione to a variety of electrophilic and
hydrophobic compounds. Human GSTs can be divided into five main
classes: Alpha, Mu, Pi, Theta, and Zeta. The theta class members
GSTT1 and GSTT2 share 55% amino acid sequence identity and both are
thought to have an important role in human carcinogenesis. The
theta genes have a similar structure, being composed of five exons
with identical exon/intron boundaries.1) Moyer, A.M., et al. Cancer Epidemiol. Biomarkers Prev. 19(3):811-821(2010)
Immunogen
This GSTT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-141 amino acids from the Central region of human GSTT2.
Western blot analysis in A549 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.