tRNA modification GTPase GTPBP3, mitochondrial, GTP-binding protein 3, Mitochondrial GTP-binding protein 1, GTPBP3, MTGP1
Product description
This locus encodes a GTP-binding protein. The encoded
protein is localized to the mitochondria and may play a role in
mitochondrial tRNA modification. Polymorphisms at this locus may be
associated with severity of aminoglycoside-induced deafness, a
disease associated with a mutation in the 12S rRNA. Alternatively
spliced transcript variants encoding different isoforms have been
described.1) Reiling, E., et al. Eur. J. Hum. Genet. 17(8):1056-1062(2009)
Immunogen
This GTPBP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 293-320 amino acids from the Central region of human GTPBP3.
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.