Application
Western blot analysis of anti-GUCY1A3 Pab in mouse brain tissue lysate (35ug/lane).Application
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma; HC = hepatocarcinoma.Application
Western blot analysis of GUCY1A3 using GUCY1A3 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the GUCY1A3 gene (Lane 2).| Product Name | Guanylyl Cyclase alpha 1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Guanylate cyclase soluble subunit alpha-3, GCS-alpha-3, GCS-alpha-1, Soluble guanylate cyclase large subunit, GUCY1A3, GUC1A3, GUCSA3, GUCY1A1 |
| Product description | Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha and a beta subunit, catalyzes the conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs.1) Saino, M., et al., Oncol. Rep. 12(1):47-52 (2004). |
| Immunogen | This Guanylyl Cyclase alpha 1 (GUCY1A3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 269-300 amino acids from the N-terminal region of human Guanylyl Cyclase alpha 1 (GUCY1A3). |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Symbol | GUCY1A3 |
|---|---|
| Alternative Names | Guanylate cyclase soluble subunit alpha-3 GCS-alpha-3 GCS-alpha-1 Soluble guanylate cyclase large subunit GUCY1A3 GUC1A3 GUCSA3 GUCY1A1 |
| Molecular Weight(MW) | 77 kDa |
Application
Western blot analysis of anti-GUCY1A3 Pab in mouse brain tissue lysate (35ug/lane).
Application
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma; HC = hepatocarcinoma.
Application
Western blot analysis of GUCY1A3 using GUCY1A3 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the GUCY1A3 gene (Lane 2).| Application Notes | For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
