Uroguanylin and guanylin (GUCA2A; MIM 139392), peptide
homologs of the bacterial heat-stable enterotoxins (e.g., the E.
coli ST toxin; STa), are endogenous activators of the guanylate
cyclase-2C receptor (GUCY2C; MIM 601330), which synthesizes cyclic
GMP (cGMP), a key component of several intracellular signal
transduction pathways.1) Yoshikawa, Y., et al. Hypertens. Res. 30(9):789-796(2007)
Immunogen
This GUCA2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-97 amino acids from the C-terminal region of human GUCA2B.
Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.